Solone (prednisolone) is an anti-inflammatory and immunosuppressant drug used for a wide range of conditions, such as:
- Allergy symptoms (e.g., angioedema, new-onset hives)
- Blood disorders (e.g., immune thrombocytopenia, warm autoimmune hemolytic anemia)
- Skin disorders
- Gastrointestinal disorders
- Inflammatory disorders
- Eye diseases
- Cancers
- Rheumatic disorders (e.g., acute gout flare, vasculitis, dermatomyositis, mixed cryoglobulinemia syndrome, polyarteritis nodosa, polymyositis, polymyalgia rheumatica, rheumatoid arthritis, systemic lupus erythematosus)
- Autoimmune nervous system disorders (e.g., acute exacerbations of multiple sclerosis)
- Kidney disorders
- Respiratory disorders (e.g., asthma)
- Endocrine disorders (e.g., primary or secondary adrenocorticoid deficiency)
- Solid organ rejection (acute/chronic)
Off-label uses (uses not approved by the Food and Drug Administration, or FDA) for Solone for adults include:
- Acute exacerbations of chronic obstructive pulmonary disease (COPD),
- Acute pericarditis
- Adjunctive therapy for moderate to severe pneumocystis pneumonias
- Alcoholic hepatitis (severe)
- Bell’s palsy
- Duchenne muscular dystrophy
- Giant cell arteritis
- Hepatitis, autoimmune
- Myasthenia gravis crisis
- Takayasu arteritis
- Thyroiditis, subacute
- Hives
What Are Side Effects of Solone Tablets?
Side effects of Solone tablets may include:
- Slow or fast heart rate
- Fluid retention (edema)
- Lightheadedness/fainting
- Acne
- Allergic dermatitis
- Stretch marks
- Sweating
- Dry scalp
- Facial redness
- Skin rash
- Thinning skin
- Thinning hair
- Hives
- Growth retardation (children)
- Excess hair growth
- Impaired glucose tolerance
- Menstrual irregularities
- Weight gain
- Hiccups
- Increased appetite
- Nausea
- Increased liver enzymes
- Headache
- Insomnia
- Feeling unwell (malaise)
- Numbness and tingling
- Spinning sensation (vertigo)
- Slow wound healing
What Are Drug Interactions of Solone Tablets?
The following is a list of drugs with which Solone tablets may interact:
- Acetylcholinesterase inhibitors
- Aldesleukin
- Amphotericin B
- Androgens
- Antacids
- Antidiabetic agents
- BCG products
- Bile acid sequestrants
- Brincidofovir
- Calcitriol
- Carbimazole
- CAR-T cell immunotherapy
- Cladribine
- Corticorelin
- Cosyntropin
- Cyclosporine
- CYP3A4 inducers and inhibitors
- Deferasirox
- Desirudin
- Desmopressin
- Estrogen derivatives
- Gallium Ga 68 dotatate
- Growth hormone analogs
- Hyaluronidase
- Immune checkpoint inhibitors
- Indium 111 capromab pendetide
- Isoniazid
- Leflunomide
- Licorice
- Loop diuretics
- Lutetium Lu 177 dotatate
- Macimorelin
- Methimazole
- Mifamurtide
- Mifepristone
- Monoclonal antibodies
- Neuromuscular-blocking agents (nondepolarizing)
- Nicorandil
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Pidotimod
- Pimecrolimus
- Polymethylmethacrylate
- Quinolones
- Ritodrine
- Salicylates
- Sargramostim
- Sipuleucel-T
- Sodium benzoate
- Sphingosine 1-phosphate (S1P) receptor modulators
- Succinylcholine
- Tacrolimus
- Talimogene laherparepvec
- Tertomotide
- Thiazide and thiazide-like diuretics
- Urea cycle disorder agents
- Vaccines (live and inactivated)
- Vitamin K antagonists (e.g., warfarin)
Always notify your doctor of all drugs and supplements you may be taking, both over-the-counter and prescription, in order to prevent any potential drug interactions with new medications.
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Reviewed on 8/31/2022
References
REFERENCES:
Image source: iStock Images
https://www.uptodate.com/contents/prednisolone-systemic-drug-information?search=solone&source=search_result&selectedTitle=2~2&usage_type=default&display_rank=2&showDrugLabel=true
Image source: iStock Images
https://www.uptodate.com/contents/prednisolone-systemic-drug-information?search=solone&source=search_result&selectedTitle=2~2&usage_type=default&display_rank=2&showDrugLabel=true