What Are the Most Common Side Effects of Cymbalta?

Cymbalta (duloxetine delayed-release capsule) is a serotonin and norepinephrine reuptake inhibitor (SNRI) used to treat major depressive disorder and other conditions. The most common side effects of Cymbalta in adults include nausea, dry mouth, drowsiness, constipation, decreased appetite, and excessive sweating.

Cymbalta (duloxetine delayed-release capsule) is a serotonin and norepinephrine reuptake inhibitor (SNRI) used to treat: 

• Major depressive disorder in adults 
• Generalized anxiety disorder in adults and pediatric patients 7 years of age and older 
• Diabetic peripheral neuropathic pain in adults 
• Fibromyalgia in adults and pediatric patients 13 years of age and older 
• Chronic musculoskeletal pain in adults 

The most common side effects of Cymbalta in adults include: 

• Nausea
• Dry mouth
• Drowsiness
• Constipation
• Decreased appetite
• Excessive sweating

The most common side effects of Cymbalta in pediatric patients include:

• Weight loss
• Decreased appetite
• Nausea
• Vomiting
• Fatigue
• Diarrhea 

Serious side effects of Cymbalta include: 

• Liver damage
• Changes in blood pressure and falls    
• Serotonin syndrome, which can be life-threatening 
• Abnormal bleeding or bruising
• Severe skin reactions
• Withdrawal symptoms
• Manic episodes
• Vision problems
• Seizures or convulsions
• Problems with urination